LifeLU
Life Language Understanding Lab
We study proteins as sequences written in the language of life. Our research uncovers the basic units, structure, and meaning encoded in molecular sequences using advances in natural language processing and computational biology.
Latest Updates
Conference ISMB Presentation Lab News
August 1, 2026
Gökçe Uludoğan and Buse Giledereli Present Their Work at ISMB 2026
Read More
Recent Publications
PUFFIN: Protein Unit Discovery with Functional Supervision
Gökçe Uludoğan, Buse Giledereli, Elif Özkırımlı and Arzucan Özgür
Bioinformatics
BibTeX
@article{uludogan2026puffin,
title={PUFFIN: Protein Unit Discovery with Functional Supervision},
author={Uludoğan, Gökçe and Giledereli, Buse and Özkırımlı, Elif and Özgür, Arzucan},
journal={Bioinformatics},
volume={42},
number={Supplement_1},
pages={btag265},
year={2026},
doi={10.1093/bioinformatics/btag265}
}
STAR-GO: Improving Protein Function Prediction by Learning to Hierarchically Integrate Ontology-Informed Semantic Embeddings
Mehmet Efe Akça, Gökçe Uludoğan, Arzucan Özgür and İnci M. Baytaş
Bioinformatics
BibTeX
@article{akca2026stargo,
title={STAR-GO: Improving Protein Function Prediction by Learning to Hierarchically Integrate Ontology-Informed Semantic Embeddings},
author={Akça, Mehmet Efe and Uludoğan, Gökçe and Özgür, Arzucan and Baytaş, İnci M.},
journal={Bioinformatics},
volume={42},
number={4},
pages={btag146},
year={2026},
doi={10.1093/bioinformatics/btag146}
}
PUMA: Discovery of Protein Units via Mutation-Aware Merging
Burak Suyunu, Özdeniz Dolu, Ibukunoluwa A. Olaosebikan, Hacer K. Bristow and Arzucan Özgür
arXiv preprint
BibTeX
@article{suyunu2025puma,
title={PUMA: Discovery of Protein Units via Mutation-Aware Merging},
author={Suyunu, Burak and Dolu, Ozdeniz and Olaosebikan, Iyanuoluwa A. and Bristow, Hannah K. and Ozgur, Arzucan},
journal={arXiv preprint arXiv:2503.08838},
year={2025}
}